INTERVENTION NO. 6

Managing Oral Ulcerations (Non-Viral) and Pain - 4

Currently, there is no drug available to prevent oral ulcerations. Several prescription and OTC agents are available to manage the pain associated with the ulcerations, and others that claim to limit the duration and severity of episodes. Recently, the FDA approved amlexanox (Aphthasol® gg) as the first topical prescription agent for the treatment of aphthous ulcers. Amlexanox is a tasteless, odorless mucoadhesive ointment, which when applied to the ulcer four times per day after meals and at bedtime, accelerates healing and reduces the size of the lesions.65 Amlexanox inhibits inflamatory mediators and has antiallergic properties.